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Manganese(salen) chloride

CAS No. 53177-12-1

Manganese(salen) chloride ( EUK-8 )

产品货号. M28316 CAS No. 53177-12-1

Manganese(salen) chloride (EUK-8), a superoxide dismutase and catalase mimetic, is an antioxidant with oxyradical scavenging properties. Manganese(salen) chloride ameliorates acute lung injury in endotoxemic swine.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
10MG ¥316 有现货
25MG ¥502 有现货
50MG ¥737 有现货
100MG ¥1077 有现货
200MG ¥1596 有现货
500MG ¥2697 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Manganese(salen) chloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Manganese(salen) chloride (EUK-8), a superoxide dismutase and catalase mimetic, is an antioxidant with oxyradical scavenging properties. Manganese(salen) chloride ameliorates acute lung injury in endotoxemic swine.
  • 产品描述
    Manganese(salen) chloride (EUK-8), a superoxide dismutase and catalase mimetic, is an antioxidant with oxyradical scavenging properties. Manganese(salen) chloride ameliorates acute lung injury in endotoxemic swine.(In Vitro):Manganese(salen) chloride (25 μM; 24-72 h) protects organotypic hippocampal slices from β-AP-induced neurotoxicity, and completely blocks β-AP-induced free radical accumulation and lipid peroxidation. (In Vivo):Manganese(salen) chloride (25 mg/kg; i.p. 3 times a week for 4 weeks) reduces cardiac oxidative stress and ameliorates pressure overload-induced heart failure in the harlequin mouse mutant . Animal Model: Wild-type (WT) and harlequin (Hq) B6CBA male and female mice Dosage: 25 mg/kg/day Administration: I.p. 3 times a week for 4 weeks Result: Prevented myocardial oxidant damage provoked by biomechanical stress. Improved survival following biomechanical stress. Prevented functional and geometrical deterioration in response to pressure overload. Attenuated necrotic and apoptotic cell death, and attenuated cardiac hypertrophy and fibrosis.
  • 同义词
    EUK-8
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    monophenolase
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    53177-12-1
  • 分子量
    356.7
  • 分子式
    C16H14ClMnN2O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    [Cl-].[Mn+5].[O-]c1ccccc1\C=[N-]\CC\[N-]=C/c1ccccc1[O-]
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Fu B, et al. Isolation and identification of flavonoids in licorice and a study of their inhibitory effects on tyrosinase. J Agric Food Chem. 2005 Sep 21;53(19):7408-14.
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